神經(jīng)生長因子(NGF)重組蛋白
Recombinant Nerve Growth Factor (NGF)
NGFB; Beta-NGF; HSAN5; NGF-B; Beta-Nerve Growth Factor
- 編號URPA105Eq01
 - 物種Equus caballus; Equine (Horse,馬) 相同的名稱,不同的物種。
 - 來源原核表達
 - 宿主E.coli
 - 內(nèi)毒素水平<1.0EU/µg(LAL法測定)
 - 亞細(xì)胞定位分泌
 - 預(yù)測分子量26.6kDa
 - 實際分子量32kDa(差異分析請參閱說明書)
 - 片段與標(biāo)簽Glu64~Ala286 with N-terminal His Tag
 - 緩沖液成份PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
 - 性狀凍干粉
 - 純度> 90%
 - 等電點10.2
 - 
                    應(yīng)用
                    Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白,請參見活性蛋白。 - 下載 英文說明書 中文說明書
 - 規(guī)格 10μg50μg 200μg 1mg 5mg
 - 價格 ¥ 498 ¥ 1245 ¥ 2490 ¥ 7470 ¥ 18675
 - 欲了解實際交易價格和更多情況,請與當(dāng)?shù)亟?jīng)銷商聯(lián)系!
 
序列
                                
                            用法
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲存
避免反復(fù)凍融。2-8°C不超過一個月,-80°C不超過12個月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定,具體方法如下:在37°C孵育48小時,沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi),在適當(dāng)?shù)臈l件下存儲,損失率低于5%。
增值服務(wù)
相關(guān)產(chǎn)品
| 編號 | 適用物種:Equus caballus; Equine (Horse,馬) | 應(yīng)用(僅供研究使用,不用于臨床診斷!) | 
| URPA105Eq01 | 神經(jīng)生長因子(NGF)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. | 
參考文獻
| 雜志 | 參考文獻 | 
| The Tohoku Journal of Experimental Medicine | Low-intensity aerobic exercise mitigates exercise-induced bronchoconstriction by improving the function of adrenal medullary chromaffin cells in asthmatic rats [Pubmed:25212248] | 
| International Journal of Pharmaceutics | Neurotrophic and antioxidant effects of silymarin comparable to 4-methylcatechol in protection against gentamicin-induced ototoxicity in guinea pigs [Pubmed:25445537] | 
| Yonsei Medical Journal | NGF and HB-EGF: Potential Biomarkers that Reflect the Effects of Fesoterodine in Patients with Overactive Bladder Syndrome [Pubmed:25510766] | 
| Molecular and Cellular Endocrinology | High glucose upregulates CYP24A1 expression which attenuates the ability of 1,25(OH)2D3 to increase NGF secretion in a rat Schwann cell line RSC96 [Pubmed:25614971] | 
| Mol Cell Endocrinol | High glucose upregulates CYP24A1 expression which attenuates the ability of 1,25(OH)2D3 [PubMed: 25614971] | 
| Neurosciences (Riyadh) | Telmisartan inhibits hyperalgesia and inflammatory progression in a diabetic neuropathic pain model of Wistar rats. [PubMed: 25864063] | 
| Neurotoxicity Research | Pro-apoptotic Action of Corticosterone in Hippocampal Organotypic Cultures [Pubmed:27189478] | 
| Psychoneuroendocrinology | Chronic mild stress influences nerve growth factor through a matrix metalloproteinase-dependent mechanism [Pubmed:26771945] | 
| Genet Mol Res | Changes in growth factor levels in the cerebrospinal fluid of autism patients after transplantation of human umbilical cord blood mononuclear cells and umbilical cord-derived mesenchymal stem cells [Pubmed:27323064] | 
| The Journal of Maternal-Fetal & Neonatal Medicine | Differential expression of cord blood neurotrophins in gestational diabetes: the impact of fetal growth abnormalities [pubmed:28081639] | 
| IOS Press Content Library | An Intranasal Formulation of Erythropoietin (Neuro-EPO) Prevents Memory Deficits and Amyloid Toxicity in the APPSwe Transgenic Mouse Model of Alzheimer's … [articles:journal-of-alzheimers-disease] | 
| biblioteca.uva | Evaluación de la secreción de factores neurotróficos por las células MSV en cocultivo con neurorretinas porcinas, en función de la dosis celular y del tiempo de cultivo [10324/27440] | 
| Progress in Neuro-Psychopharmacology & Biological Psychiatry | Antidepressant drugs for beta amyloid-induced depression: A new standpoint? [pubmed:28499898] | 
| Osteoarthritis and Cartilage | Mechanical loading of intervertebral disc modulates microglia proliferation, activation, and chemotaxis [Pubmed:29723636] | 
| Stem?Cell?Research?&?Therapy | Autophagy is required for human umbilical cord mesenchymal stem cells to improve spatial working memory in APP/PS1 transgenic mouse model [Pubmed:29335016] | 
| Pharmacological?Research? | N-3 PUFA diet enrichment prevents amyloid beta-induced depressive-like phenotype [Pubmed:29203442] | 
| Experimental Neurology | Preterm umbilical cord blood derived mesenchymal stem/stromal cells protect preterm white matter brain development against hypoxia-ischemia [Pubmed:30012511] | 
| Biochemical Pharmacology | Effects of n-3 PUFA enriched and n-3 PUFA deficient diets in na?ve and Aβ-treated female rats [Pubmed:30028991] | 
| Experimental Dermatology | 3‐‐Laurylglyceryl ascorbate improves the development of sensitive skin through the reduction of oxidative stress [Pubmed: 30698879] | 
| BioMed Research International | Administration of Repetitive Transcranial Magnetic Stimulation Attenuates Aβ1-42-Induced Alzheimer's Disease in Mice by Activating β-Catenin Signaling [] | 
| International Journal of Ophthalmology | A novel xeno-free culture system for human retinal pigment epithelium cells [Pubmed: 31024807] | 
| Experimental and Therapeutic Medicine | Involvement of neurotrophic signaling in doxorubicin?induced cardiotoxicity [Pubmed: 32010279] | 
| Open Access Macedonian Journal of Medical Sciences | Inhibition of Receptor for Advanced Glycation End Products as New Promising Strategy Treatment in Diabetic Retinopathy [Pubmed: 32165929] | 
| MOLECULAR NUTRITION & FOOD RESEARCH | Hyperlipidemia Down‐Regulate Brain Antioxidant Defense Enzymes and Neurotrophins in Rats: Assessment of the Modulatory Potential of EPA+ DHA and?… [Pubmed: 32918393] | 
| Neuropharmacology | Impaired LTD-like motor cortical plasticity in female patients with major depression disorder [Pubmed: 32791084] | 
| COLLOIDS AND SURFACES B-BIOINTERFACES | Effects of gold nanoparticles administration through behavioral and oxidative parameters in animal model of parkinson's disease [Pubmed: 32777662] | 
| 博士論文 | Neurobiological determinants of depressive-like symptoms in rodents [] | 
| Medical Research Journal | Changes of substance P, NGF and CGRP salivary levels among patients undergoing physical therapy [] | 
| Journal of the Taiwan Institute of Chemical Engineers | Multiple-component dual-phase solid lipid nanoparticles with conjugated transferrin for formulating antioxidants and nerve growth factor against neuronal apoptosis [] | 
| EUROPEAN CHILD & ADOLESCENT PSYCHIATRY | Increased serum brain-derived neurotrophic factor and adrenocorticotropic hormone levels are associated with obsessive compulsive disorder in medication?free??- [33389158] | 
| DRUG DEVELOPMENT RESEARCH | Neuroprotective effect of Na+/H+?exchangers isoform?\1 inactivation against 6?\hydroxydopamine?\induced mitochondrial dysfunction and neuronal apoptosis in Parkinson's disease models [33538000] | 
| BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | Sea urchin gangliosides exhibit neuritogenic effects in neuronal PC12 cells via TrkA- and TrkB-related pathways [33589896] | 
| Neuropsychiatr Dis Treat | Repetitive Transcranial Magnetic Stimulation Improves Mild Cognitive Impairment Associated with Alzheimer's Disease in Mice by Modulating the miR-567?… [34239303] | 
| Pharmaceuticals (Basel) | Carissa macrocarpa Leaves Polar Fraction Ameliorates Doxorubicin-Induced Neurotoxicity in Rats via Downregulating the Oxidative Stress and Inflammatory Markers [34959705] | 
| Cell Biochem Funct | CNTs‐CaP/chitosan‐coated AZ91D magnesium alloy extract promoted rat dorsal root ganglia neuron growth via activating ERK signalling pathway [34296452] | 
| Carbohydrate Polymers | Gene delivery of chitosan-graft-polyethyleneimine vectors loaded on scaffolds for nerve regeneration [Pubmed:35550777] | 
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